TESSERA GRC is the world's first clinician-led adherence science consortium. We fund scholarships, govern research standards, connect investigators across 60+ countries, and build the evidence infrastructure that makes precision adherence science possible everywhere — not just where funding flows.
An estimated 125,000 deaths and $300 billion in avoidable healthcare costs occur annually in the United States alone — not from treatment failure, but from patients not taking their medications as prescribed.
Between 30% and 50% of patients with chronic conditions do not adhere to their prescribed regimens. Yet most interventions treat all non-adherence the same — a critical error with measurable consequences.
Scala Carta Foundation exists to change that by funding and disseminating the research infrastructure that makes precise, behavioral phenotyping of non-adherence possible at scale.
Driven by beliefs, distrust, perceived side effects, or calculated risk. Requires motivational and behavioral intervention, not reminders.
Caused by forgetfulness, complexity, access barriers, or system failures. Requires structural support and simplification.
MAP (Multidimensional Adherence Parameters) is the validated instrument that distinguishes INA from UNA, generating PEACS phenotypes that drive targeted intervention. Independently authored by Philip Morisky and deployed through ATLAS, MAP is the shared measurement standard that TESSERA GRC is built around.
Scala Carta Foundation funds researchers, stewards global data standards, and connects clinicians and scientists across 62+ countries. TESSERA GRC (Global Research Consortium) is the program through which this work is organized. ATLAS is the data collection platform members use at their tier.
Full TESSERA membership fee waivers for graduate students and researchers at institutions in World Bank-classified low- and middle-income countries. No external funding required. No cost, no barrier.
A data-exchange pathway for researchers whose institutions restrict external platform subscriptions. Submit standardized aggregate MAP data and receive full instrument access, a formal letter of permission, and TESSERA authorship credit.
A live collaboration board for the global adherence community. Post active studies, call for international co-investigators, announce grant opportunities, and discover matching cohorts across 40+ countries. Research Affiliate tier and above can post.
Formal partnership agreements with universities, health ministries, pharmacy networks, clinical research organizations, and pharmaceutical manufacturers. TESSERA partnerships establish data-sharing frameworks, co-publication terms, and advisory governance roles.
TESSERA governs the world's only multi-site, multi-country MAP normative dataset. Members contribute aggregate data; TESSERA publishes validated phenotype benchmarks under open-access terms that any researcher can cite, replicate, or build on.
TESSERA GRC establishes the governance, risk, and compliance framework for how MAP data is held, attributed, and shared across jurisdictions including the EU (GDPR), UAE (PDPL), and US (HIPAA). Institutions joining TESSERA inherit this framework — they do not have to build it themselves.
A no-login, browser-based kiosk tool for pharmacies, mobile outreach programs, and telehealth services to administer MAP assessments outside of clinical settings. Available to Institutional Partner members and above. Assessments contribute to the global adherence dataset under TESSERA data governance.
Every TESSERA member receives a formal credential tied to their tier and active membership. These credentials appear in publications, thesis acknowledgments, grant applications, and researcher CVs — and are verifiable against the TESSERA member registry.
The inaugural TESSERA Summit will convene member institutions, researchers, and industry partners for the first global conference dedicated exclusively to behavioral adherence phenotyping science. One agenda. One network. Every major contributor to this field in the same room.
TESSERA membership includes access to the ATLAS platform at every tier. Members who want standalone platform access without consortium membership can get a workspace key at atlas.adherence.cc.
The global burden of medication non-adherence falls disproportionately on low- and middle-income countries, where chronic disease rates are rising fastest and research infrastructure is thinnest. TESSERA GRC was designed with this asymmetry in mind.
Through our LMIC Grant Pathway and Research Contribution License (RCL), researchers at qualifying institutions can access full TESSERA membership, including MAP instrument access and co-authorship on normative studies, at no cost.
Donor support is what makes this possible. Every contribution to Scala Carta Foundation directly funds the participation of a researcher who would otherwise be excluded from the global evidence network.
Full TESSERA membership fee waiver for researchers at institutions in World Bank-classified low- and middle-income countries.
Researchers anywhere may contribute normative MAP data in exchange for full consortium membership, including institutional access to MAP scoring and co-authorship eligibility.
Every tier grants consortium standing, data governance coverage, and a TESSERA credential. The tier you choose reflects the scope of your engagement — from a single researcher earning their first publication credit, to a health system contributing to global normative science, to an industry partner accessing population-level real-world adherence data. All tiers include ATLAS platform access for data collection.
Every institution's cohort is isolated. Your patient records never mix with another member's data. What contributes to the global normative dataset is anonymized aggregate MAP output — phenotype distributions and domain scores, stripped of all identifiers.
The TESSERA Data Governance Charter defines how MAP data is attributed, retained, and shared across jurisdictions. Member institutions inherit this framework on entry — they do not rebuild it from scratch for each study.
Request the Data Governance Charter →TESSERA data processing for EU member institutions operates under a documented lawful basis. Data subject rights, retention limits, and processor agreements are covered in the Charter.
Gulf-region members operate under the UAE Personal Data Protection Law framework. TESSERA maintains separate processing records for GCC jurisdictions.
US clinical and research sites using MAP through ATLAS receive an IRB-ready data dictionary and BAA template on request. De-identified aggregate outputs do not trigger HIPAA obligations.
Population-level adherence insights delivered to Industry Partners are PEACS phenotype distributions and domain-level aggregate scores. No raw records, no PII, no individual patient data. Segmented by indication, country, and care setting on request.
Post active studies, call for international co-investigators, and discover matching cohorts across 40+ countries. Research Affiliate tier and above can post; all tiers can browse and respond to open calls.
View in ATLAS ↗Scala Carta Foundation is a 501(c)(3) pending non-profit. Your donation supports LMIC researcher access, MAP validation studies, and the open evidence infrastructure that makes precision adherence science possible.
Funds one month of MAP instrument access for an LMIC researcher who cannot afford the membership fee.
Donate $100Sponsors a full Student tier membership for a graduate researcher in an LMIC country for one year.
Donate $500Funds a validation study partnership covering MAP instrument deployment, data collection support, and co-authorship in a normative dataset publication.
Donate $2,500Endows a named LMIC fellowship for one year, covering full Validation Partner membership for a researcher in a qualifying country.
Donate $10,000For wire transfer, institutional giving, or custom amounts, contact philip.morisky@scalacartafoundation.org
Scala Carta Foundation · 501(c)(3) pending · EIN issued · All donations are pending tax-deductibility
From inquiry to active membership in under two weeks for most tiers. No complex procurement process. No lengthy onboarding forms.
Fill out the membership application below with your institution, country, research focus, and preferred tier. Applications are reviewed within 1–2 business days for LMIC Research Grant applicants, and 3–5 business days for all others.
Scala Carta Foundation issues your formal TESSERA membership confirmation, credential letter, TESSERA Study ID, data governance agreement, and — for tiers that include it — your ATLAS workspace key provisioned for your data residency region. LMIC scholarship recipients receive a fee waiver letter alongside their membership package.
Post to the Research Exchange. Complete MAP certification. Add your TESSERA credential to your CV and publications. Begin contributing assessments to the global normative dataset. Institutional and above members can activate the Community Gateway for pharmacy and outreach sites.
Whether you are a single researcher, a teaching hospital, a medical or health sciences school, or a global pharmaceutical company, TESSERA GRC has a tier built for your scope of work. Every member adds one more tile to the first true map of global medication adherence.
Applications are reviewed within 5 business days. You will receive an ATLAS workspace access code and a formal membership confirmation from the Scala Carta Foundation.
Thank you for applying to TESSERA GRC. Your application has been submitted to the Scala Carta Foundation for review. A confirmation email will arrive within 24 hours, and a membership decision within 1–2 business days for LMIC applicants, or up to 5 business days for all others.